South Carolina wine trails

• Native muscadine and scuppernong grapes, sweet and thick-skinned, are the traditional base for many South Carolina wines, per Discover South Carolina.
• Some wineries now also make drier styles, such as Italian-style Sangiovese, alongside muscadine wines.
• Silver Dew Winery on Daufuskie Island, described by Discover South Carolina as the state's first winery, operates from a former lighthouse wick house.

Checked October 1, 2026.

All wine trails in South Carolina

No organized wine trail with its own website or official tourism page as of October 1, 2026. Know one? Email us and we will check it.

“Wineries” is the count the trail itself publishes. “Unconfirmed” means we found it only on older or third-party pages.